Domoticz

Should the Zigbee2MQTT base topic match the auto discovery prefix in Domoticz ?

TIA

from the wiki https://www.domoticz.com/wiki/Zigbee2MQTT
in MQTT

Set Auto Discovery topic field, (default = homeassistant) or as set in HomeAssistant_discovery_topic in Zigbee2MQTT settings earlier.

what do you mean with base topic?
There is a autodiscovery topic and a state topic in Zigbee2MQTT (see also the screenshot in the wiki).