Domoticz

I just put a rfxtrx 433 on my Raspberry pi4 but i can not save the setup (see picture) also there are a lot of usb ports available in setup. Which one to choose? When i do Dmesg i got
usb 1-1.3: new full-speed USB device number 3 using xhci_hcd
[52983.923535] usb 1-1.3: New USB device found, idVendor=0403, idProduct=6001, bcdDevice= 6.00
[52983.923550] usb 1-1.3: New USB device strings: Mfr=1, Product=2, SerialNumber=3
[52983.923563] usb 1-1.3: Product: RFXtrx433
[52983.923575] usb 1-1.3: Manufacturer: RFXCOM
[52983.923587] usb 1-1.3: SerialNumber: A1UTW1VF
[52984.007834] usbcore: registered new interface driver usbserial_generic
[52984.007862] usbserial: USB Serial support registered for generic
[52984.018064] usbcore: registered new interface driver ftdi_sio
[52984.018096] usbserial: USB Serial support registered for FTDI USB Serial Device
[52984.018198] ftdi_sio 1-1.3:1.0: FTDI USB Serial Device converter detected
[52984.018260] usb 1-1.3: Detected FT232RL
[52984.019852] usb 1-1.3: FTDI USB Serial Device converter now attached to ttyUSB0
I also have a aeon labs stick gen 5 zwave on the rasp (also not working)

And now the Domoticz gives 8080/#/Offline

Did you ever find out how to fix this? I have the same problem